RCAN2 Antibody, Biotin conjugated

Code CSB-PA618879LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RCAN2 Polyclonal antibody
Uniprot No.
Target Names
RCAN2
Alternative Names
Calcipressin 2 antibody; Calcipressin-2 antibody; CSP2 antibody; Down syndrome candidate region 1-like 1 antibody; Down syndrome critical region gene 1 like 1 protein antibody; DSCR1L1 antibody; MCIP2 antibody; Myocyte enriched calcineurin interacting protein 2 antibody; Myocyte-enriched calcineurin-interacting protein 2 antibody; RCAN2 antibody; RCAN2_HUMAN antibody; RCN2 antibody; Regulator of calcineurin 2 antibody; Thyroid hormone responsive gene ZAKI4 antibody; Thyroid hormone responsive protein ZAKI4 antibody; thyroid hormone-responsive (skin fibroblasts) antibody; Thyroid hormone-responsive protein ZAKI-4 antibody; ZAKI4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Calcipressin-2 protein (88-197AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Gene References into Functions
  1. RCAN2 expression is upregulated in human masticatory mucosa during wound healing PMID: 28005267
  2. our data have elucidated the molecular and cellular mechanism whereby PGF(2alpha) regulates CXCL8 expression via the FP receptor in endometrial adenocarcinomas and have highlighted RCAN1-4 as a negative regulator of CXCL8 expression PMID: 19819266
  3. the expression of ZAKI-4 isoforms is subjected to distinct hormonal as well as tissue-specific regulation, constituting a complex signalling network through inhibition of calcineurin. PMID: 12102656
  4. DSCR1-L1 is constitutively expressed in endothelial cells and acts similar to DSCR1 in inhibiting calcineurin activity and restraining VEGF-mediated angiogenesis. PMID: 17610901
Protein Families
RCAN family
Tissue Specificity
Expressed in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas.
Database Links

HGNC: 3041

OMIM: 604876

KEGG: hsa:10231

STRING: 9606.ENSP00000329454

UniGene: Hs.440168

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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